Edição genética e CRISPR: estamos preparados para suas implicações éticas?

Conteúdo do artigo principal

Jorge Hernández Navas
Juan Therán Leon

Detalhes do artigo

Seção
Editorial

Referências

Howard HC, Van El CG, Forzano F, Radojkovic D, Rial-Sebbag E, De Wert G, et al. One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans. Eur J Hum Genet. 2018;26(1):1–11. https://doi.org/10.1038/s41431-017-0024-z

Piergentili R, Del Rio A, Signore F, Umani RF, Marinelli E, Zaami S. CRISPR-Cas and Its Wide-Ranging Applications: From Human Genome Editing to Environmental Implications, Technical Limitations, Hazards and Bioethical Issues. Cells. 2021;10(5). https://doi.org/10.3390/cells10050969

Coller BS. Ethics of Human Genome Editing. Annu Rev Med. 2019;70:289–305. https://doi.org/10.1146/annurev-med-112717-094629

Ormond KE, Mortlock DP, Scholes DT, Bombard Y, Brody LC, Faucett WA, et al. Human Germline Genome Editing. Am J Hum Genet. 2017;101(2):167–76. https://doi.org/10.1016/j.ajhg.2017.06.012

Greenfield A. Making sense of heritable human genome editing: Scientific and ethical considerations. Prog Mol Biol Transl Sci. 2021;182:1–28. https://doi.org/10.1016/bs.pmbts.2020.12.008