Microinfusão de metotrexato nas lesões de couro cabeludo podem auxiliar no alívio da alopécia frontal fibrosante?
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Conteúdo do artigo principal
Resumo
Introdução: A alopecia frontal fibrosante é forma de alopecia cicatricial linfocítica primária, com perda de pelos na linha de implantação frontal do couro cabeludo e outras áreas corporais. Consiste em doença sistêmica e multifatorial, com influência genética, hormonal, ambiental, racial e, por vezes, de gênero. A técnica de microinfusão de micropartículas através da pele (MMP®) é minimamente invasiva e pouco dolorosa ou indolor.
Objetivo: Revisar a eficácia dessa técnica com metotrexato na alopecia frontal fibrosante.
Método: A revisão da literatura foi feita colhendo informações publicadas em plataformas virtuais buscada por descritores relacionados ao tema, identificados por meio do DeCS, como: “alopecia frontal fibrosante, líquen plano pilar, calvície, couro cabeludo, e metotrexato” com busca AND ou OR, considerando o título e/ou resumo. Após, considerando-se somente os que tinham maior relação ao tema, foi realizada a leitura da íntegra dos textos.
Resultados: Foram incluídos XX artigos.
Conclusão: A aplicação de MTX por MMP® mostrou redução significativa dos sintomas associados à alopecia frontal fibrosante, e melhora nas medidas frontoglabelares e frontotemporais. A técnica mostrou-se segura e foi bem tolerada.
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Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
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