O impacto da obesidade nos resultados pós-operatórios de operações abdominais
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Resumo
Introdução: Espondilite anquilosante ou espondilite axial radiográfica é uma espondiloartrite axial com predominância masculina, cujos sintomas incluem dor lombar baixa associada a rigidez matinal podendo evoluir para anquilose. Sua causa inflamatória está associada à alteração estrutural, o que pode influir na clínica, funcionalidade e resposta ao tratamento. Objetivo: Revisar se a composição corporal de pacientes com espondilite anquilosante tem influência nos parâmetros inflamatórios de acordo com o sexo. Método: Foi desenvolvida busca no PubMed para identificar a literatura disponível. Os critérios incluíram os termos “Paradoxo da Obesidade”, combinado com critérios adicionais de busca incluindo os termos “cirurgia geral, cirurgia abdominal e resultados” para melhor definir a pesquisa. Os critérios foram restritos às línguas inglesa e portuguesa e pacientes adultos. Artigos originais, revisões sistemáticas e metanálises foram considerados para inclusão. Os estudos elegíveis foram inicialmente identificados por título e resumo. Resultado: Foram incluídos 41 artigos. Conclusão: Embora alguns grupos ainda necessitem estudos adicionais para comprovar o real efeito da obesidade nos resultados pós-operatórios, outros já possuem validade bem estabelecida. Contudo, ficou demonstrado que a obesidade contribuiu para o aumento dos parâmetros de atividade inflamatória em pacientes do sexo masculino com espondilite anquilosante.
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