Temporal-spatial analysis of mortality from Lupus in Brazil, between 2011 and 2021
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Abstract
Introduction: Systemic Lupus Erythematosus (SLE) has a global epidemiology marked by variations in prevalence that can be attributed to genetic, environmental, and socioeconomic factors. It predominantly affects women of childbearing age. Studies have shown that its prevalence is higher in Black and Asian populations, while white populations have lower rates.
Objective: To analyze mortality from in Brazil between 2011 and 2021, taking into account its temporal-spatial distribution.
Method: It was developed under the descriptive epidemiological scope and based on data extracted from the Mortality Information System (SIM/DATASUS). Variables such as sex, age group, ethnicity, marital status, education, place of death, and residence were analyzed. The temporal trend was assessed by joinpoint regression, and the spatial distribution was assessed by Global and local Moran indices.
Result: Between 2011 and 2021, 11,195 deaths from SLE were recorded, representing an average mortality rate of 0.49/100,000 inhabitants, with a predominance of women (89%) and a higher incidence in individuals aged 40-49 years (19.46%). The highest rates were in the South, Southeast, and Central-West regions. The analysis demonstrated positive autocorrelation and significant clusters in the aforementioned regions.
Conclusion: Regional disparities exist, and specific strategies to expand access to early diagnosis and appropriate treatment are needed, especially in vulnerable regions.
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