Epidemiological profile of patients with acute kidney disease and COVID-19 in the first wave of the pandemic in Brazil

Abstract

Introduction: COVID-19 is a multisystem disease that can affect the renal system, resulting in worse outcomes. Objective: To analyze the prevalence of acute kidney failure (AKI) in patients with COVID-19. Method: Cross-sectional study to analyze the relationship of the disease with sex, age, comorbidities, comparing with control group. Results: Medical records of patients hospitalized for SARS-CoV-2 were analyzed, divided into without kidney injury and with kidney injury - with and without hemodialysis. About 15% developed AKI as a complication, 9.5% with hemodialysis. Length of stay and mechanical ventilation, rates of pulmonary involvement, need for ICU, urea and creatinine values were worse in patients with AKI, and mortality was higher in the group with AKI and hemodialysis (86%). The prevalence of ARI in patients with COVID-19 was higher in those over 50 years of age, in men and in those with arterial hypertension. Conclusion: Patients with AKI had worse outcomes and a greater number of complications.