Quando o corpo se volta contra si: um caso marcante de síndrome antissintetase com anti-Jo-1 positivo

Conteúdo do artigo principal

Rafaely Cristine dos Santos
Tailine Fontanella Galvani
Giovanna Jorge Sabino
Fernanda Nicoly Jobins Jarentchuk
Thelma Larocca Skare

Resumo

.

Detalhes do artigo

Seção
Relato de Caso

Referências

Hochberg MC, et al. Rheumatology. 7th ed. Philadelphia: Elsevier; 2019.

Zulfiqar B, Aksionav P, Bittar M, Chapman C. A case of Anti-Jo-1 myositis with unique biopsy findings. Case Rep Rheumatol. 2022;2022:9096643. https://doi.org/10.1155/2022/9096643

Li JC, Lai ZH, Shao M, Jin YB, Gao XJ, Zhang K, et al. Significance of anti-Jo-1 antibody's clinical stratification in idiopathic inflammatory myopathy and disease spectrum. Beijing Da Xue Xue Bao Yi Xue Ban. 2023;55(6):958–65. https://doi.org/10.19723/j.issn.1671-167X.2023.06.002

Liu CH, Kor CT, Hung MH, Hsiao KH, Cheng YH, Tien YC. Differences in the clinical characteristics and 1-year mortality rates of patients with dermatomyositis with anti-Jo-1 and anti-MDA5 antibodies. J Immunol Res. 2023;2023:2988422. https://doi.org/10.1155/2023/2988422

Andrade VP, De Souza FHC, Pinto GLB, Shinjo SK. The relevance of anti-Jo-1 autoantibodies in patients with definite dermatomyositis. Adv Rheumatol. 2021;61(1):12. https://doi.org/10.1186/s42358-021-00171-x.

Notarnicola A, Preger C, Lundström SL, Renard N, Wigren E, Gompel EV, et al. Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome. Arthritis Res Ther. 2022;24(1):62. https://doi.org/10.1186/s13075-022-02745-6

Lundberg IE, Fugimoto M, Vencovsky J, Aggarwal R, Holmqvist M, Christopher-Stine L, et al. Idiopathic inflammatory myopathies. Nat Rev Dis Primers. 2021;7(1):86. https://doi.org/10.1038/s41572-021-00321-x

Connors GR, Christopher-Stine L, Oddis CV, Danoff SK. Interstitial lung disease associated with the idiopathic inflammatory myopathies: what progress has been made in the past 35 years? Chest. 2010;138(6):1464–74. https://doi.org/10.1378/chest.10-0180

Nishaikai M, Reichlin M. Heterogeneity of precipitating antibodies in polymyositis and dermatomyositis: characterization of the Jo-1 antibody system. Arthritis Rheum. 1980;23(8):881–8. doi: https://doi.org/10.1002/art.1780230802

Yang H, Chen Q, Sun C, Jin Q, Zhang L, Liu Q, et al. Clinical and prognostic associations of anti-Jo-1 antibody levels in patients with antisynthetase syndrome. Respir Res. 2024;25(1):222. doi: https://doi.org/10.1186/s12931-024-02851-w

Galindo-Feria AS, Albrecht I, Fernandes-Cerqueira C, Notarnicola A, James EA, Herrath J, et al. Proinflammatory histidyl-transfer RNA synthetase-specific CD4+ T cells in the blood and lungs of patients with idiopathic inflammatory myopathies. Arthritis Rheumatol. 2020;72(1):179–91. doi: https://doi.org/10.1002/art.41075

Xu Z, Wei Z, Zhou JJ, Ye F, Loo WS, Wang F, et al. Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing. Structure. 2012;20(9):1470–7. doi: https://doi.org/10.1016/j.str.2012.08.001